TravaCor

Product Overview

Key ingredients

Taurine: Neuroprotective amino acid that provides antioxidant protection and demonstrates GABA-A agonist activity ^(1-3).^† GABA is the primary inhibitory neurotransmitter in the brain important for calm and sleep ^(4-6).

L-theanine: Amino acid that acts as a glutamate receptor antagonist ^(7)†. In a randomized, double-blind, placebo-controlled study, L-theanine was shown to significantly reduce stress ^(8)†.

5-HTP (from Griffonia simplicifolia seed extract): 5-hydroxytryptophan (5-HTP) crosses the blood-brain barrier and is a precursor to serotonin and melatonin ⁽⁹⁾.^† Serotonin is important for regulating mood and sleep-wake function ⁽¹⁰⁾. In a randomized, double-blind study, 5-HTP was shown to significantly improve mood ⁽¹¹⁾.^†

Vitamins B and C: Active forms of vitamin B6, folate, B12, and C are important for serotonin synthesis ^(12-16).^†

References
1. Kumari N, et al. Adv Exp Med Biol. 2013;775:19-27.
2. Shimada K, et al. Adv Exp Med Biol. 2015;803:581-96.
3. Kletke O, et al. PLoS One. 2013;8(4):e61733.
4. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
5. Mohler H. Neuropharmacology. 2012;62(1):42-53.
6. Saper C, et al. Nature. 2005;437(7063):1257-63.
7. Kakuda T, et al. Biosci Biotechnol Biochem. 2002;66(12):2683-2686.
8. Kimura K, et al. Biol Psychol. 2007; 74(1):39-45.
9. Shaw K, et al. Cochrane Database Syst Rev. 2002;(1):CD003198.
10. Monti J. Sleep Med Rev. 2011;15(4):269-81.
11. Jangid P, et al. Asian J Psychiatr. 2013;6(1):29-34.
12. Dakshinamurti K, et al. Ann N Y Acad Sci. 1990;585:128-44.
13. Bottiglieri T. Psychiatr Clin North Am. 2013;36(1):1-13.
14. Stahl S. J Clin Psychiatry. 2008;69(9):1352-3.
15. Antoniades C, et al. Circulation. 2006;114(11):1193-201.
16. May J, et al. Brain Res Bull. 2013;90:35-42.